The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Mar. 26, 2021
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

The Trustees of the University of Pennsylvania, Philadelphia, PA (US);

Inventors:

Christopher S. Chen, Newton, MA (US);

Jan D. Baranski, Philadelphia, PA (US);

Ritika Chaturvedi, Philadelphia, PA (US);

Michael T. Yang, West Windsor, NJ (US);

Kelly R. Stevens, Seattle, WA (US);

Sangeeta N. Bhatia, Lexington, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/44 (2015.01); A61L 27/50 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/40 (2006.01);
U.S. Cl.
CPC ...
A61L 27/50 (2013.01); A61K 35/44 (2013.01); A61L 27/225 (2013.01); A61L 27/24 (2013.01); A61L 27/3604 (2013.01); A61L 27/3804 (2013.01); A61L 27/3808 (2013.01); A61L 27/3834 (2013.01); A61L 27/3839 (2013.01); A61L 27/3886 (2013.01); A61L 27/40 (2013.01); A61L 27/507 (2013.01); A61L 2430/20 (2013.01); A61L 2430/28 (2013.01);
Abstract

The present disclosure provides patterned biomaterials having organized cords and extracellular matrix embedded in a 3D scaffold. According, the present disclosure provides compositions and applications for patterned biomaterials. Pre-patterning of these biomaterials can lead to enhanced integration of these materials into host organisms, providing a strategy for enhancing the viability of engineered tissues by promoting vascularization.


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