The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Sep. 10, 2018
Applicant:
Portland State University, Portland, OR (US);
Inventor:
Marilyn Mackiewicz, Portland, OR (US);
Assignee:
Portland State University, Portland, OR (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/69 (2017.01); A61K 49/00 (2006.01); A61P 35/00 (2006.01); A61K 49/04 (2006.01); A61K 49/18 (2006.01); A61K 9/51 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/6911 (2017.08); A61K 9/5115 (2013.01); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); A61K 49/0084 (2013.01); A61K 49/0093 (2013.01); A61K 49/0428 (2013.01); A61K 49/1812 (2013.01); A61K 49/1824 (2013.01); A61K 49/1839 (2013.01); A61K 49/1845 (2013.01); A61P 35/00 (2018.01); B82Y 5/00 (2013.01);
Abstract
Disclosed herein are embodiments of nanoparticle composites that comprise covalently coupled stabilizing agent molecules that improve stability of the nanoparticle composites and allow for tight packing of lipids and/or membranes. The nanoparticle composites can further comprise inhibition inhibitors and/or lipid components that interact to form a hybrid lipid bilayer membrane around the nanoparticle core. The nanoparticle composites can be coupled to drugs, targeting moieties, and imaging moieties. The nanoparticle composites can be used for in vivo drug deliver, disease diagnosis/treatment, and imaging.