The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
Jun. 03, 2017
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
Or A. Shemesh, Somerville, MA (US);
Changyang Linghu, Cambridge, MA (US);
Edward Boyden, Chestnut Hill, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/405 (2006.01); A61K 41/00 (2020.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); C12N 5/0793 (2010.01); C12N 13/00 (2006.01); C12N 15/86 (2006.01); G01N 33/50 (2006.01); G01N 33/566 (2006.01); A61N 5/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); A61K 38/17 (2013.01); A61N 5/06 (2013.01); A61N 5/062 (2013.01); C07K 14/405 (2013.01); C07K 14/4716 (2013.01); C07K 14/705 (2013.01); C07K 14/70571 (2013.01); C12N 5/0619 (2013.01); C12N 13/00 (2013.01); C12N 15/86 (2013.01); G01N 33/5058 (2013.01); G01N 33/566 (2013.01); A61K 38/00 (2013.01); C07K 2319/01 (2013.01);
Abstract
The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to target opsins to the soma of cells in which they are expressed. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects.