The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 10, 2022
Filed:
May. 04, 2018
Applicants:
Zealand Pharma A/s, Søborg, DK;
Boston Medical Center Corporation, Boston, MA (US);
Inventors:
Bjarne Due Larsen, Roskilde, DK;
Ulrik Mouritzen, Rungsted Kyst, DK;
Dongjoon Kim, Boston, MA (US);
Sayon Roy, Boston, MA (US);
Assignees:
ZEALAND PHARMA A/S, Glostrup, DK;
BOSTON MEDICAL CENTER CORPORATION, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2019.01); A61P 3/10 (2006.01); A61K 31/40 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 31/40 (2013.01); A61P 3/10 (2018.01);
Abstract
The use of gap junction intercellular communication (GJIC) modulators in the treatment or prevention of diabetic eye disease is disclosed, and more particularly to their use for the treatment or prevention of early stage diabetic retinopathy and diabetic macular edema by inhibiting apoptosis of retinal endothelial cells and inhibiting pericyte loss.