The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Jan. 05, 2018
Applicant:

Mbc Pharma, Inc., Aurora, CO (US);

Inventors:

Shawn Zinnen, Aurora, CO (US);

Alexander Karpeisky, Aurora, CO (US);

Assignee:

MBC PHARMA, INC., Aurora, CO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7068 (2006.01); A61P 19/08 (2006.01); A61P 35/04 (2006.01); A61K 31/337 (2006.01); A61K 51/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7068 (2013.01); A61K 31/337 (2013.01); A61K 51/0491 (2013.01); A61P 19/08 (2018.01); A61P 35/04 (2018.01);
Abstract

Provided herein is a novel method for creating fixed, non-antagonistic molar ratios of drugs in and around the bone environment for desired periods of time. This method enables treating bone and bone-related disease by administering a pharmaceutical composition comprising a bone-targeted therapeutic agent able to release a drug payload from the bone surface, in addition to a second therapeutic agent. Such methods are useful in the treatment of bone and bone-related diseases, such as cancer-induced bone disease, osteomyelitis and bone infection, bone pain and inflammatory bone disease, metabolic disease, as well as others.


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