The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Mar. 06, 2017
Applicants:

Osaka University, Suita, JP;

National Institute for Materials Science, Tsukuba, JP;

Nippon Zoki Pharmaceutical Co., Ltd., Osaka, JP;

Inventors:

Hiroyuki Tanaka, Suita, JP;

Kiyoshi Okada, Suita, JP;

Hideki Yoshikawa, Suita, JP;

Koji Suzuki, Suita, JP;

Mitsuhiro Ebara, Tsukuba, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/70 (2006.01); A61K 47/34 (2017.01); A61K 47/36 (2006.01); A61K 31/714 (2006.01); A61K 35/36 (2015.01); A61K 45/00 (2006.01); A61K 38/18 (2006.01); A61P 25/02 (2006.01); A61K 47/32 (2006.01);
U.S. Cl.
CPC ...
A61K 9/7007 (2013.01); A61K 9/70 (2013.01); A61K 31/714 (2013.01); A61K 35/36 (2013.01); A61K 38/18 (2013.01); A61K 38/185 (2013.01); A61K 45/00 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); A61K 47/36 (2013.01); A61P 25/02 (2018.01);
Abstract

Provided is a sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet comprising a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.


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