The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 10, 2022

Filed:

Aug. 21, 2017
Applicant:

Miraki Innovation Think Tank Llc, Cambridge, MA (US);

Inventors:

Christopher Velis, Cambridge, MA (US);

Karen Miller, Cambridge, MA (US);

Assignee:

MIRAKI INNOVATION THINK TANK LLC, Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 8/04 (2006.01); A61K 8/19 (2006.01); A61K 8/34 (2006.01); A61M 5/19 (2006.01); A61M 5/315 (2006.01); A61M 5/44 (2006.01); A61M 5/46 (2006.01); A61Q 19/08 (2006.01); A61Q 19/06 (2006.01); A61P 17/10 (2006.01); A61K 8/02 (2006.01);
U.S. Cl.
CPC ...
A61K 8/044 (2013.01); A61K 8/0204 (2013.01); A61K 8/19 (2013.01); A61K 8/345 (2013.01); A61M 5/19 (2013.01); A61M 5/3158 (2013.01); A61M 5/44 (2013.01); A61M 5/46 (2013.01); A61P 17/10 (2018.01); A61Q 19/06 (2013.01); A61Q 19/08 (2013.01); A61K 2800/81 (2013.01); A61K 2800/91 (2013.01);
Abstract

The present invention is directed to targeted delivery of a cold slurry underneath a patient's skin to improve the cosmetic appearance of the skin. The 'target' tissue can be muscle tissue that when cooled cannot contract and cause wrinkles/lines in the skin to appear. The target tissue can also be adipose tissue that causes overlying tissue to sag and form wrinkles/lines. The cold slurry induces apoptosis, and reduces the size of the tissue, and causes the connective tissue supporting the skin to thicken and tighten, thereby reducing wrinkles/lines. Skin can also be tightened with cold slurry injected into the dermis layer of the skin or within the layers of the oral mucosa making a cold slurry treatment ideal for reducing the appearance of baggy skin after a patient loses weight and or for treating obstructive sleep apnea. Cold slurry can also be used to treat cellulite and acne.


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