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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11320431 B1

PDFFull Text
Date of Patent:
May. 03, 2022

Filed:

Jun. 27, 2017

Combination of reversible and irreversible cell labeling for analizing receptor-ligand krate

Applicants:

Technische Universitaet Muenchen, Munich, DE;

Juno Therapeutics Gmbh, Munich, DE;

Inventors:

Magdalena Nauerth, Munich, DE;

Dirk Busch, Schliersee, DE;

Lothar Germeroth, Goettingen, DE;

Assignees:

TECHNISCHE UNIVERSITAET MUENCHEN, Munich, DE;

JUNO THERAPEUTICS GMBH, Munich, DE;

Attorneys:

Acuity Law Group, PC

Michael A. Whittaker

Primary Examiner:

Changhwa J Cheu

Int. Cl.
CPC ...
G01N 33/557 (2006.01); G01N 33/566 (2006.01); G01N 33/543 (2006.01); G01N 33/50 (2006.01); C07K 14/74 (2006.01); C12Q 1/04 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
G01N 33/557 (2013.01); C07K 14/70539 (2013.01); C12N 5/0636 (2013.01); C12Q 1/04 (2013.01); G01N 33/502 (2013.01); G01N 33/543 (2013.01); G01N 33/566 (2013.01); C07K 2319/22 (2013.01); G01N 2458/00 (2013.01);
Abstract

The invention relates to a method of determining the dissociation rate constant (k) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein the cell has bound to it such a combination of cell labeling. The invention further relates to a kit and an apparatus useful in performing the methods of the invention. The invention further relates to a method of isolation a high-avidity T cell.

Find Patent Forward Citations

Nauerth, Magdalena. (2022). Combination of reversible and irreversible cell labeling for analizing receptor-ligand krate (U.S. Patent No. 11320431). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11320431

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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