The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Oct. 11, 2017
Applicant:
Olipass Corporation, Yongin-si, KR;
Inventors:
Shin Chung, Yongin-si, KR;
Daram Jung, Hwaseong-Si, KR;
Bongjun Cho, Yongin-Si, KR;
Heungsik Yoon, Seongnam-Si, KR;
Kangwon Jang, Yongin-Si, KR;
Assignee:
OliPass Corporation, Yongin-si, KR;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3181 (2013.01); C12N 2310/333 (2013.01); C12N 2310/336 (2013.01); C12N 2320/30 (2013.01);
Abstract
Provided are peptide nucleic acid derivatives targeting a part of the human HIF-1α pre-mRNA. The peptide nucleic acid derivatives potently induce exon skipping to yield splice variants of HIF-1α mRNA in cells, and are useful to treat indications or conditions involving the overexpression of HIF-1α.