The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Nov. 16, 2017
Applicant:
Beijing Hanmi Pharmaceutical Co., Ltd., Beijing, CN;
Inventors:
Jiawang Liu, Beijing, CN;
Nanmeng Song, Beijing, CN;
Yaping Yang, Beijing, CN;
Maengsup Kim, Beijing, CN;
Assignee:
BEIJING HANMI PHARMACEUTICAL CO., LTD., Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/30 (2013.01); C07K 16/32 (2013.01); C07K 16/46 (2013.01); C07K 2317/31 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01);
Abstract
Provided are an anti-PD-1/anti-HER2 natural antibody structural heterodimeric bispecific antibody and a method of preparing the same. Specifically, provided are a highly stable anti-PD-1/anti-HER2 heterodimeric bispecific antibody having characteristics of a natural IgG and having no mismatched heavy chain and light chain, and a method of preparing the same. The bispecific antibody may bind to both of two kinds of target molecules, and thus may be more effective in treating complex diseases.