The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Jul. 10, 2020
Applicant:
Masonic Medical Research Laboratory, Utica, NY (US);
Inventor:
Zhiqiang Lin, Utica, NY (US);
Assignee:
MASONIC MEDICAL RESEARCH LABORATORY, Utica, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4705 (2013.01); C12N 15/86 (2013.01); C12N 2750/14143 (2013.01); C12N 2830/001 (2013.01);
Abstract
Provided is a polynucleotide, including a cis-regulatory element and a nucleotide sequence encoding a vestigial like 4 protein, wherein the cis-regulatory element includes an uncoupling protein 1 enhancer and an uncoupling protein 1 promoter. Also provided is a viral vector including said polynucleotide. Also provided is a method of transfecting a cell or a subject with said polynucleotide or said viral vector.