The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Oct. 18, 2018
Bayer Aktiengesellschaft, Leverkusen, DE;
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Marcus Koppitz, Berlin, DE;
Holger Siebeneicher, Berlin, DE;
Nico Bräuer, Falkensee, DE;
Elisabeth Pook, Wuppertal, DE;
Andrea Rotgeri, Berlin, DE;
Roland Neuhaus, Berlin, DE;
Oliver Martin Fischer, Berlin, DE;
Jens Nagel, Daxweiler, DE;
Adam James Davenport, Abingdon, GB;
James Lindsay Carr, Abingdon, GB;
Robert James Townsend, Abingdon, GB;
Nina Connelly Ursinyova, Abingdon, GB;
Shelley Anne Parrott, Abingdon, GB;
Bayer Aktiengesellschaft, Leverkusen, DE;
Bayer Pharma Aktiengesellschaft, Berlin, DE;
Abstract
The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R, Rand Rare as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.