The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Mar. 13, 2018
Applicant:
Gwangju Institute of Science and Technology, Gwangju, KR;
Inventors:
Yong Chul Kim, Gwangju, KR;
Young Hwan Jung, Gwangju, KR;
Assignee:
GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY, Gwangju, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/80 (2006.01); A61P 23/00 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 213/80 (2013.01); A61P 23/00 (2018.01); C07D 401/12 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01);
Abstract
The present invention relates to novel 5-hydroxy pyridine-based compounds useful as P2X1 and P2X3 receptor antagonists and compositions comprising the same. The compounds according to the present invention have an activity of strongly antagonizing P2X1 and P2X3 receptors, and thus can be effectively used as a drug for treating or preventing chronic inflammatory diseases or neuropathic pain diseases caused by P2X1 and P2X3 receptor activity.