The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2022

Filed:

Nov. 17, 2017
Applicant:

Kansas State University Research Foundation, Manhattan, KS (US);

Inventors:

Christopher T. Culbertson, Manhattan, KS (US);

Stefan H. Bossmann, Manhattan, KS (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B81B 5/00 (2006.01); B01L 3/00 (2006.01); C07K 1/22 (2006.01); C07K 1/28 (2006.01); G01N 1/30 (2006.01); G01N 1/34 (2006.01); G01N 1/38 (2006.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); B01L 3/50273 (2013.01); C07K 1/22 (2013.01); C07K 1/28 (2013.01); G01N 1/30 (2013.01); G01N 1/34 (2013.01); G01N 1/38 (2013.01); B01L 2200/0647 (2013.01); B01L 2400/043 (2013.01); B82Y 30/00 (2013.01); G01N 2001/388 (2013.01);
Abstract

Microfluidic devices and nanobiosensors comprising a magnetic nanoparticle attached to a reporter molecule via a release unit for microfluidic-based detection of a target analyte in a biological sample. The nanobiosensors can be magnetically manipulated or guided through the microfluidics channels for incubation with the biological sample, concentration of the nanobiosensors, and detection of target analytes, without having to pump the entire initial sample through a microfluidic channel of the microfluidic device. The magnetic nanoparticles are separated from the reporter molecules before detection and can be re-used.


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