The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 03, 2022

Filed:

Nov. 06, 2018
Applicants:

Massachusetts Institute of Technology, Cambridge, MA (US);

Seattle Children's Hospital, Seattle, WA (US);

Inventors:

Omid Veiseh, Bellaire, TX (US);

Robert S. Langer, Newton, MA (US);

Daniel G. Anderson, Framingham, MA (US);

William Shain, Kirkland, WA (US);

Brian W. Hanak, Seattle, WA (US);

Samuel R. Browd, Mercer Island, WA (US);

Robert F. Hevner, La Jolla, CA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61L 29/08 (2006.01); A61L 29/16 (2006.01); G01N 33/68 (2006.01); A61L 31/06 (2006.01); A61L 27/34 (2006.01); A61L 29/06 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01); A61L 27/18 (2006.01); A61L 27/54 (2006.01); A61M 27/00 (2006.01);
U.S. Cl.
CPC ...
A61L 29/08 (2013.01); A61L 27/18 (2013.01); A61L 27/34 (2013.01); A61L 27/54 (2013.01); A61L 29/06 (2013.01); A61L 29/085 (2013.01); A61L 29/16 (2013.01); A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01); A61L 2300/41 (2013.01); A61L 2400/18 (2013.01); A61L 2420/02 (2013.01); A61M 27/002 (2013.01); A61M 2205/0238 (2013.01);
Abstract

Neurological implants whose surfaces have been chemically and covalently modified to impart beneficial properties to the neurological implants are described. The neurological implants possess improved biocompatibility compared to a corresponding neurological implant that lacks the chemical modification. Following implantation in a subject, the surface-modified neurological implants induce a lower-foreign body response, compared to a corresponding unmodified product.


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