The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
Jun. 04, 2015
Cedars-sinai Medical Center, Los Angeles, CA (US);
Dan Gazit, Los Angeles, CA (US);
Edward M. Schwarz, Rochester, NY (US);
Hyun Bae, Los Angeles, CA (US);
Gadi Pelled, Los Angeles, CA (US);
Zulma Gazit, Los Angeles, CA (US);
Dmitriy Sheyn, Los Angeles, CA (US);
Wafa Tawackoli, Beverly Hills, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
Described herein are methods and compositions using PTH and mesenchymal stem cells (MSCs) for treatment of osteoporosis, bone fractures, and related conditions. Administration of both PTH and MSCs leads to increased homing of MSCs to sites of vertebral bone and rib fracture. The described methods and compositions provide therapeutic approaches that rely, in-part, on stem cell capacity for regeneration and repair. The potential for enhanced bone formation and fracture repair may allow for both preventative and palliative treatments in osteoporotic patients, with combined PTH+MSC therapy producing bone regeneration capacity that is significantly superior to either treatment alone.