The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 2022
Filed:
May. 17, 2017
Vanderbilt University, Nashville, TN (US);
Alex G. Waterson, Murfreesboro, TN (US);
Jason R. Abbott, Nashville, TN (US);
J. Phillip Kennedy, Nashville, TN (US);
Stephen W. Fesik, Nashville, TN (US);
Qi Sun, Vernon Hills, IL (US);
Jason Phan, Nashville, TN (US);
Michael C. Burns, Chicago, IL (US);
Pratiq Patel, Nashville, TN (US);
Vanderbilt University, Nashville, TN (US);
Abstract
The present invention relates to quinazoline compounds and compositions that modulate Ras signaling. Compounds and compositions of the present invention are useful in the treatment of cancers and other disease states associated with Ras dysfunction (e.g., Ras-associated autoimmune leukoproliferative disorder, or certain types of mitochondrial dysfunction) in a subject, for example a mammal or a human.