The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

Mar. 02, 2017
Applicants:

Toagosei Co., Ltd., Tokyo, JP;

National University Corporation Nagoya University, Aichi, JP;

Inventors:

Nahoko Baileykobayashi, Tsukuba, JP;

Makoto Sawada, Nagoya, JP;

Tetsuhiko Yoshida, Tsukuba, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 27/62 (2021.01); G16H 50/30 (2018.01); G16H 50/20 (2018.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6818 (2013.01); G01N 27/62 (2013.01); G01N 33/6848 (2013.01); G01N 33/6851 (2013.01); G01N 33/6896 (2013.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); C07K 7/00 (2013.01); G01N 2800/28 (2013.01);
Abstract

The method for aiding ALS detection provided by the present invention includes determining a profile of signal peptides contained in a bodily fluid from a test subject, and comparing the signal peptide profile thus determined for the test subject with a previously-determined profile of signal peptides in a bodily fluid from a healthy subject. The presence of a difference between the signal peptide profile of the test subject and the signal peptide profile of the healthy subject at a specific molecular weight is then associated with the test subject's suffering from or developing ALS.


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