The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Nov. 10, 2017
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Tohoku University, Sendai, JP;
Makoto Inada, Tokushima, JP;
Keiko Kawata, Tokushima, JP;
Kimiyoshi Sudoh, Takarazuka, JP;
Hideki Katagiri, Sendai, JP;
Tetsuya Yamada, Sendai, JP;
Kei Takahashi, Sendai, JP;
OTSUKA PHARMACEUTICAL CO., LTD., Tokyo, JP;
TOHOKU UNIVERSITY, Sendai, JP;
Abstract
An object of the disclosure is to provide a composition for evaluating the hepatic glucose uptake capacity of a subject and a method for evaluating the hepatic glucose uptake capacity of a subject with the composition. An object of the disclosure is to provide a method for determining the stage of pre-onset diabetes in a subject with pre-onset diabetes using the method for evaluating the hepatic glucose uptake capacity. An aspect of the disclosure accordingly provides a composition comprisingC-labeled glucose for evaluating the hepatic glucose uptake capacity of a subject. Another aspect of the disclosure provides a method comprising measuringC-labeled glucose in a blood sample or an expired air sample obtained from the subject to which the composition was administered. The desired evaluation or determination can be achieved by comparing the measured value with a reference value.