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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11312943 B1

PDFFull Text
Date of Patent:
Apr. 26, 2022

Filed:

Jan. 29, 2018

Abhd5 and partial hdac4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases

Applicant:

Ruprecht-karls-universität Heidelberg, Heidelberg, DE;

Inventors:

Johannes Backs, Dossenheim, DE;

Zegeye Jebessa, Heidelberg, DE;

Lorenz Lehmann, Heidelberg, DE;

Hugo Katus, Heidelberg, DE;

Oliver Müller, Dossenheim, DE;

Assignee:

RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG, Heidelberg, DE;

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

Maria Marvich

Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12N 15/12 (2006.01); A61K 38/48 (2006.01); C12N 9/80 (2006.01); C12N 9/10 (2006.01); A61K 38/45 (2006.01); A61K 38/50 (2006.01); C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1029 (2013.01); A61K 38/45 (2013.01); A61K 38/48 (2013.01); A61K 38/50 (2013.01); C12N 9/80 (2013.01); C12Q 1/48 (2013.01); C12Y 203/01051 (2013.01); C12Y 305/01098 (2013.01); G01N 2333/91057 (2013.01); G01N 2500/04 (2013.01); G01N 2500/20 (2013.01);
Abstract

The present invention relates to Abhydrolase containing domain 5 (ABHD5) and N-terminal fragments of HDAC4 (HDAC4-NT) and variants of the aforementioned peptides for the treatment and prevention of heart failure. The present invention further provides vectors for the cardiomyocyte-specific expression of said peptides and a test system comprising ABHD5 for the identification of novel compounds which are useful for the treatment of heart failure.

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Backs, Johannes. (2022). Abhd5 and partial hdac4 fragments and variants as a therapeutic approach for the treatment of cardiovascular diseases (U.S. Patent No. 11312943). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11312943

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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