The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

Jul. 30, 2018
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Saso Cemerski, Norfolk, MA (US);

Jared N. Cumming, Winchester, MA (US);

Johnny E. Kopinja, Newton, MA (US);

Samanthi A. Perera, Lexington, MA (US);

Benjamin Wesley Trotter, Medfield, MA (US);

Archie Ngai-chiu Tse, Long Island City, NY (US);

Inventors:

Saso Cemerski, Norfolk, MA (US);

Jared N. Cumming, Winchester, MA (US);

Johnny E. Kopinja, Newton, MA (US);

Samanthi A. Perera, Lexington, MA (US);

Benjamin Wesley Trotter, Medfield, MA (US);

Archie Ngai-Chiu Tse, Long Island City, NY (US);

Assignee:

MERCK SHARP & DOHME CORP., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 31/381 (2006.01); A61K 39/00 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 31/381 (2013.01); A61P 35/00 (2018.01); A61K 2039/505 (2013.01);
Abstract

Therapeutic combinations that comprise at least one antagonist of the Programmed Death 1 receptor (PD-1) and at least one benzo[b]thiophene compound that activates the Stimulator of Interferon Genes (STING) pathway are disclosed herein. Also disclosed is the use of such therapeutic combinations for the treatment of cancers.


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