The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Jun. 23, 2017
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Ronald Bradley Demattos, Zionsville, IN (US);
Michael Carl Irizarry, Carmel, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 25/28 (2006.01); A61K 39/395 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/3955 (2013.01); A61P 25/28 (2018.01); A61K 2039/545 (2013.01); C07K 2317/24 (2013.01); C07K 2317/92 (2013.01);
Abstract
The invention is directed to a short term induction treatment with anti-N3pGlu Aβ antibodies of a disease characterized by deposition of Aβ in the brain, that include Alzheimer's disease (AD), Down's syndrome, and cerebral amyloid angiopathy (CAA). In certain embodiments, patients are administered an induction dose of 10 to 60 mg/kg of an anti-N3pGlu Aβ antibody for a period of 6 months or less.