The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Aug. 18, 2017
Applicant:
National University of Singapore, Singapore, SG;
Inventors:
Manjunatha Ramachandra Kini, Singapore, SG;
Sindhuja Sridharan, Chennai, IN;
Assignee:
National University of Singapore, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/58 (2006.01); C07K 4/12 (2006.01); A61P 9/00 (2006.01); A61P 9/12 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/58 (2013.01); A61P 9/00 (2018.01); A61P 9/12 (2018.01); C07K 4/12 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to peptides with vasodilatory and/or diuretic functions. In particular, the invention relates to modifying key amino acid residues in natriuretic peptides to achieve different functions and properties. Accordingly the invention also includes modified natriuretic peptides. The invention also relates to the use of these peptides for regulating blood pressure-volume and/or treating a heart condition.