The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

May. 24, 2017
Applicant:

Rijksuniversiteit Groningen, Groningen, NL;

Inventors:

Giovanni Maglia, Glimmen, NL;

Carsten Wloka, Hohen Neuendorf, DE;

Natalie Lisa Mutter, Groningen, NL;

Misha Soskine, Paris, FR;

Gang Huang, Groningen, NL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/26 (2006.01); C07K 14/435 (2006.01); C12Q 1/6869 (2018.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01); G01N 33/48 (2006.01); C12Q 1/68 (2018.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
C07K 14/43595 (2013.01); C12Q 1/6869 (2013.01); G01N 27/44791 (2013.01); G01N 33/48721 (2013.01); B82Y 5/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/21 (2013.01); C07K 2319/22 (2013.01);
Abstract

The invention relates generally to the field of nanopores and the use thereof in various applications, such as analysis of biopolymers and macromolecules, typically by making electrical measurements during translocation through a nanopores. Provided is a system comprising a funnel-shaped proteinaceous nanopore comprising an a-helical pore-forming toxin that is a member from the actinoporin protein family, more in particular Fragaceatoxin C (FraC), a mutant FraC, a FraC paralog, or a FraC homolog.


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