The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Jul. 22, 2019
Applicant:
Simon Fraser University, Burnaby, CA;
Inventors:
Assignee:
SIMON FRASER UNIVERSITY, Burnaby, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/572 (2006.01); C07F 9/38 (2006.01); A61K 47/54 (2017.01); A61P 19/08 (2006.01);
U.S. Cl.
CPC ...
C07F 9/572 (2013.01); A61K 47/548 (2017.08); A61P 19/08 (2018.01); C07F 9/3873 (2013.01);
Abstract
The present invention relates to EP4 agonist-bisphosphonate conjugates or related compounds and uses thereof. Said conjugates or related compounds may be used to provide delivery of an EP4 agonist or related compound to a desired site of action, such as a bone. Bisphosphonate moieties, linked to the EP4 agonists via amide linkers, have been implicated in the inhibition of bone resorption and bone targeting.