The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

Mar. 15, 2018
Applicants:

Jiangsu Hengrui Medicine Co., Ltd., Jiangsu, CN;

Shanghai Hengrui Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Biao Lu, Shanghai, CN;

Shenglan Wang, Shanghai, CN;

Xiaodong Shen, Shanghai, CN;

Feng He, Shanghai, CN;

Weikang Tao, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 403/14 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01);
Abstract

A heteroaryl[4,3-c]pyrimidin-5-amine derivative, a preparation method therefor, and medical uses thereof are provided. Specifically, a heteroaryl[4,3-c]pyrimidin-5-amine derivative of formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and uses thereof as therapeutic agents are provided. In particular, the provided compounds can be used as Areceptor antagonists and for treatment of conditions or symptoms that are ameliorated by inhibiting the Areceptor. The various substituent groups in the formula (I) have the meanings as described in the specification.


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