The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Apr. 27, 2018
Texas Children's Hosptial, Houston, TX (US);
Texas Heart Institute, Houston, TX (US);
Darren Woodside, Pearland, TX (US);
Peter Vanderslice, Houston, TX (US);
Robert Market, Houston, TX (US);
Ronald Biediger, Houston, TX (US);
Richard Dixon, Houston, TX (US);
James T. Willerson, Houston, TX (US);
Ananth Annapragada, Houston, TX (US);
Eric Tanifum, Houston, TX (US);
Texas Heart Institute, Houston, TX (US);
Texas Children's Hospital, Houston, TX (US);
Abstract
Disclosed herein is a composition comprising a plurality of liposomes having an average diameter of less than 400 nanometers, wherein the plurality of liposomes comprise: a first lipid or phospholipid; a second lipid or phospholipid which is derivatized with a polymer; and a sterically bulky excipient capable of stabilizing the liposomes; a third lipid or phospholipid derivatized with a polymer terminated with an integrin targeting component; DSPE or a fourth lipid or phospholipid derivatized with a group binding a contrast enhancing agent wherein the plurality of liposomes optionally encapsulates a payload component consisting of one or more bioactive agents.