The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

Apr. 17, 2017
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Sergei Zolotukhin, Gainesville, FL (US);

Sean M. Crosson, Gainesville, FL (US);

Cedrick Shawn Dotson, Gainesville, FL (US);

Seth Currlin, Gainesville, FL (US);

Andres Acosta, Rochester, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 38/26 (2006.01); C07K 14/47 (2006.01); C07K 14/575 (2006.01); C07K 14/605 (2006.01); A61K 48/00 (2006.01); A61K 9/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 9/0053 (2013.01); A61K 38/22 (2013.01); A61K 38/2207 (2013.01); A61K 38/26 (2013.01); A61K 48/0058 (2013.01); C07K 14/47 (2013.01); C07K 14/575 (2013.01); C07K 14/57563 (2013.01); C07K 14/605 (2013.01); C12N 15/86 (2013.01); C12N 2750/14142 (2013.01); C12N 2750/14143 (2013.01);
Abstract

The present application provides methods and compositions for AAV-mediated delivery of PYY and Glucagon-like Peptide 1 or an analog thereof (e.g., Exendin-4) to a subject (e.g., the saliva of a subject). In some embodiments, compositions and methods for topical delivery of Ex-4 and PYY peptides also are provided. Methods and compositions are useful to promote weight loss and/or altered lipid taste sensitivity, as well as for the treatment of diabetes.


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