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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11311624 B1

PDFFull Text
Date of Patent:
Apr. 26, 2022

Filed:

Aug. 08, 2018

Inhibitors of mek/pi3k, jak/mek, jak/pi3k/mtor and mek/pi3k/mtor biological pathways and methods for improving lymphatic uptake, bioavailability, and solubility of therapeutic compounds

Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Brian D. Ross, Ann Arbor, MI (US);

Marcian Van Dort, Ann Arbor, MI (US);

Assignee:

THE REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);

Attorney:

Marshall, Gerstein & Borun LLP

Primary Examiner:

Joseph R Kosack

Int. Cl.
CPC ...
A61K 47/60 (2017.01); A61K 47/54 (2017.01); C07C 259/10 (2006.01); C07D 239/48 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 47/54 (2017.08); C07C 259/10 (2013.01); C07D 239/48 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 471/04 (2013.01);
Abstract

Inhibitors of mTOR, MEK, JAK and PI3K and compositions containing the same are disclosed. Methods of using the inhibitors in the treatment of a variety of diseases and conditions wherein inhibition of one or more of mTOR, MEK, JAK and PI3K provides a benefit also are disclosed. Methods of using chemical attachment moieties and linkers for the purposes of modifying compound solubility and/or lymphatic absorption are also disclosed.

Find Patent Forward Citations

Ross, Brian. (2022). Inhibitors of mek/pi3k, jak/mek, jak/pi3k/mtor and mek/pi3k/mtor biological pathways and methods for improving lymphatic uptake, bioavailability, and solubility of therapeutic compounds (U.S. Patent No. 11311624). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11311624

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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