logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11311583 B1

PDFFull Text
Date of Patent:
Apr. 26, 2022

Filed:

Jul. 23, 2018

Treatment methods using adenovirus

Applicant:

Vascular Biogenics Ltd., Modiin, IL;

Inventors:

Eyal Breitbart, Hashmonaim, IL;

Andrea Leubitz, Efrat, IL;

Erez Feige, Hemed, IL;

Richard Penson, Braintree, MA (US);

Assignee:

Vascular Biogenetics Ltd., Modiin, IL;

Attorney:

Sterne, Kessler, Goldstein & Fox P.L.L.C.

Primary Examiner:

Shin Lin Chen

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12N 15/79 (2006.01); C07H 21/04 (2006.01); A61K 35/761 (2015.01); C12N 15/86 (2006.01); C07K 14/705 (2006.01); A61K 31/337 (2006.01); A61K 31/713 (2006.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/761 (2013.01); A61K 9/0019 (2013.01); A61K 31/337 (2013.01); A61K 31/713 (2013.01); A61K 45/06 (2013.01); A61K 48/00 (2013.01); A61K 48/0058 (2013.01); C07K 14/70503 (2013.01); C07K 14/70578 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/10332 (2013.01); C12N 2800/24 (2013.01); C12N 2830/008 (2013.01);
Abstract

The invention provides methods of reducing or decreasing a size of a tumor or eliminating a tumor by inhibiting, decreasing, or reducing neo-vascularization or angiogenesis in a tumor in a patient by administering an adenovirus comprising a nucleic acid construct comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter. Also provided is a homogeneous population of an adenovirus comprising a FAS-chimera gene operably linked to an endothelial cell-specific promoter and its uses thereof.

Find Patent Forward Citations

Breitbart, Eyal. (2022). Treatment methods using adenovirus (U.S. Patent No. 11311583). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11311583

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…