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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11311541 B1

PDFFull Text
Date of Patent:
Apr. 26, 2022

Filed:

Apr. 09, 2015

Treatment of gvhd

Applicants:

Kadmon Corporation, Llc, New York, NY (US);

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Alexandra Zanin-Zhorov, Staten Island, NY (US);

Bruce Robert Blazar, Golden Valley, MN (US);

Ryan Flynn, Minneapolis, MN (US);

Assignees:

KADMON CORPORATION, LLC, New York, NY (US);

REGENTS OF THE UNIVERSITY OF MINNESOTA, Minneapolis, MN (US);

Attorney:

Fox Rothschild LLP

Primary Examiner:

Shobha Kantamneni

Int. Cl.
CPC ...
A61K 31/50 (2006.01); A61K 31/506 (2006.01); C07D 401/12 (2006.01); C07D 239/42 (2006.01); C07D 491/052 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 498/04 (2006.01); C07D 495/04 (2006.01); C07D 239/30 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 417/14 (2006.01); C07D 491/048 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01); C07D 513/04 (2006.01); C07D 487/04 (2006.01); C07D 409/14 (2006.01); C07D 239/48 (2006.01); C07D 239/47 (2006.01); A61K 31/519 (2006.01); A61K 31/517 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); A61K 31/551 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/551 (2013.01); C07D 239/30 (2013.01); C07D 239/42 (2013.01); C07D 239/47 (2013.01); C07D 239/48 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01); C07D 495/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The invention relates to treatment of graft versus host disease (GVHD) using compounds that inhibit ROCK2. In preferred aspects, the present invention provides methods for the treatment of GVHD, including chronic GVHD (cGVHD) using compounds having the formulae 1-XXV, as set forth herein.

Find Patent Forward Citations

Zanin-Zhorov, Alexandra. (2022). Treatment of gvhd (U.S. Patent No. 11311541). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11311541

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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