The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 26, 2022
Filed:
Mar. 15, 2019
Applicants:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Michael D. Altman, Needham, MA (US);
Matthew L. Childers, Medfield, MA (US);
James P. Jewell, Newton, MA (US);
Charles A. Lesburg, Waban, MA (US);
Tony Siu, Brookline, MA (US);
Inventors:
Michael D. Altman, Needham, MA (US);
Matthew L. Childers, Medfield, MA (US);
James P. Jewell, Newton, MA (US);
Charles A. Lesburg, Waban, MA (US);
Tony Siu, Brookline, MA (US);
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/10 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 411/04 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); A61K 31/4725 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01); A61K 31/538 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4725 (2013.01); A61K 31/497 (2013.01); A61K 31/538 (2013.01); A61K 31/5377 (2013.01); C07D 405/10 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 411/04 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract
The instant invention provides compounds of formula I which are STING inhibitors, and as such are useful for the treatment of STING-mediated diseases such as inflammation, asthma, COPD and cancer.