The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 26, 2022

Filed:

Oct. 31, 2019
Applicant:

The University of Memphis Research Foundation, Memphis, TN (US);

Inventors:

Jessica Amber Jennings, Memphis, TN (US);

Daniel Lee Baker, Memphis, TN (US);

Rukhsana Awais, Memphis, TN (US);

Zoe Harrison, Memphis, TN (US);

Babatunde Raji, Memphis, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); A61P 1/02 (2006.01); A01N 37/08 (2006.01); A61K 47/36 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/19 (2013.01); A01N 37/08 (2013.01); A61K 47/36 (2013.01); A61P 1/02 (2018.01); A61P 31/04 (2018.01);
Abstract

Compositions and methods for using cyclopropanated structural analogs of fatty acid biofilm dispersal agents are characterized by superior biofilm dispersion. When used in combination with antimicrobials, these analogs decrease the minimum inhibitory concentration of antimicrobial agents required for eradication of the biofilm and/or treatment of infection. Methods for using these analogs include direct application to a surface, blending with lipid based carriers, or covalent anchoring the molecule to a surface. Typically, the cyclopropanated structural analog has the structure according to formula (I):


Find Patent Forward Citations

Loading…