The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2022
Filed:
Apr. 25, 2019
Applicant:
Deutsches Rheuma-forschungszentrum Berlin, Berling, DE;
Inventors:
Assignee:
DEUTSCHES RHEUMA-FORSCHUNGSZENTRUM BERLIN, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/58 (2006.01); G01N 33/543 (2006.01); G01N 33/566 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/585 (2013.01); G01N 33/54313 (2013.01); G01N 33/566 (2013.01); G01N 33/56972 (2013.01); G01N 2458/15 (2013.01); G01N 2560/00 (2013.01);
Abstract
Beads for use as a control, calibration and/or quantification probe in a mass cytometry assay, wherein the beads are labeled with a heavy metal selected from the group comprising osmium or ruthenium. Also disclosed are beads labeled with a heavy metal exhibiting a surface functionalization that allows for the binding of an affinity reagent, such as a metal-conjugated antibody. Methods are described for the labeling of the beads and usage of the beads for quantification of cell surface receptors or for a compensation of channel crosstalk in mass cytometry assays.