The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Mar. 19, 2019
Applicant:

University of Central Florida Research Foundation, Inc., Orlando, FL (US);

Inventors:

Jesus Manuel Perez, Orlando, FL (US);

Atul Asati, Oviedo, FL (US);

Santimukul Santra, Orlando, FL (US);

Charalambos Kaittanis, Oviedo, FL (US);

Sudip Nath, West Bengal, IN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/543 (2006.01); G01N 33/94 (2006.01); B82Y 15/00 (2011.01); B01J 31/26 (2006.01); G01N 33/574 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54346 (2013.01); B01J 31/26 (2013.01); B82Y 15/00 (2013.01); G01N 33/5432 (2013.01); G01N 33/57423 (2013.01); G01N 33/582 (2013.01); G01N 33/587 (2013.01); G01N 33/9413 (2013.01); B01J 2231/005 (2013.01);
Abstract

Methods, systems, compositions include biocompatible polymer coated nanoceria that function as aqueous redox catalyst with enhanced activity at an acidic to moderately alkaline pH value between 1 and 8. The compositions are used as oxidizing agents for decomposition, decontamination or inactivation of organic contaminants, such as, pesticides and chemical warfare agents. Another use includes nanoceria as targetable nanocatalyst prepared by conjugating various targeting ligands to the nanoparticle coating to form a colorimetric or fluorescent probe in immunoassays and other molecule binding assays that involve the use of a molecule in solution that changes the color of the solution or emits a fluorescent signal, where localization of nanoceria to organs or tissue is assessed by treatment with an oxidation sensitive dye or other detection devices. Versatility and uses of the nanoceria compositions are controlled by pH value, choice of dye substrate and thickness of the polymer coating on the ceria nanoparticles.


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