The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Jul. 24, 2020
Applicant:

Cysbio Aps, Hørsholm, DK;

Inventors:

Christian Bille Jendresen, Copenhagen, DK;

Solvej Siedler, Kokkedal, DK;

Steen Gustav Stahlhut, Frederiksberg, DK;

Alex Toftgaard Nielsen, Rungsted Kyst, DK;

Assignee:

CYSBIO APS, Kgs. Lyngby, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/42 (2006.01); C12N 9/88 (2006.01);
U.S. Cl.
CPC ...
C12P 7/42 (2013.01); C12N 9/88 (2013.01); C12Y 403/01023 (2013.01);
Abstract

The present invention generally relates to the field of biotechnology as it applies to the production of hydroxycinnamic acids using polypeptides having tyrosine ammonia lyase activity. More particularly, the present invention pertains to polypeptides having tyrosine ammonia lyase activity and high substrate specificity towards tyrosine, which makes them particularly suitable in the production of p-coumaric acid and other hydroxycinnamic acids. The present invention thus provides processes for the production of p-coumaric acid and other hydroxycinnamic acids employing these polypeptides as well as recombinant host cells expressing same.


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