The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Nov. 05, 2018
Applicant:

Nextera As, Oslo, NO;

Inventors:

Geir Åge Løset, Drøbak, NO;

Terje Frigstad, Skjeberg, NO;

Sebastian Berge-Seidl, Oslo, NO;

Nicolay Rustad Nilssen, Vollen, NO;

Inger Sandlie, Oslo, NO;

Assignee:

NEXTERA AS, Oslo, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C12N 15/70 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); C12N 15/1037 (2013.01); C40B 40/08 (2013.01); C07K 2319/43 (2013.01); C12N 2795/00022 (2013.01);
Abstract

The present invention provides a vector construct comprising the following components: (i) a sequence encoding a signal peptide which directs proteins into the Tat secretory pathway; and (ii) a sequence encoding a fluorophore fused to a sequence encoding a pVIII phage coat protein. Nucleic acid molecules comprising components (i) and (ii) are also provided, together with phage particles comprising such vectors or nucleic acid molecules and expressing a fluorophore-pVIII fusion protein on the surface. Methods for producing such fluorescent phage particles are also provided.


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