The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2022
Filed:
Dec. 09, 2019
Sanofi Biotechnology, Paris, FR;
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Marie Baccara-Dinet, Paris, FR;
Corinne Hanotin, Paris, FR;
Laurence Bessac, Paris, FR;
Umesh Chaudhari, Bridgewater, NJ (US);
Robert C. Pordy, Tarrytown, NY (US);
William J. Sasiela, Tarrytown, NY (US);
Daniel A. Schwemmer Gipe, Tarrytown, NY (US);
SANOFI BIOTECHNOLOGY, Paris, FR;
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Abstract
The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to patients with heterozygous familial hypercholesterolemia a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating patients with heterozygous familial hypercholesterolemia who are not adequately controlled by maximum tolerated dose statin therapy with or without other lipid lowering therapy.