The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Jun. 29, 2018
Applicant:

Bebetter Med Inc., Guangdong, CN;

Inventors:

Xiong Cai, Guangzhou, CN;

Changgeng Qian, Guangzhou, CN;

Chunqiang Ye, Guangzhou, CN;

Qijie He, Guangzhou, CN;

Assignee:

BEBETTER MED INC., Guangdong, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); C07D 307/80 (2006.01); C07D 263/56 (2006.01); C07D 307/83 (2006.01); C07D 327/06 (2006.01); C07D 327/04 (2006.01); C07D 307/85 (2006.01); C07D 317/54 (2006.01); C07D 491/048 (2006.01); C07D 277/64 (2006.01); C07D 333/54 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); C07D 263/56 (2013.01); C07D 277/64 (2013.01); C07D 307/80 (2013.01); C07D 307/83 (2013.01); C07D 307/85 (2013.01); C07D 317/54 (2013.01); C07D 327/04 (2013.01); C07D 327/06 (2013.01); C07D 333/54 (2013.01); C07D 491/048 (2013.01);
Abstract

Provided are a 1,3-di-substituted ketene compound having a structure as represented by formula (I) and an application thereof. Such a type of compound primarily activates peroxisome proliferator-activated receptor (PPAR) α, and also activates PPPAδ and PPPAγ. The compound may be used to treat various diseases associated with PPAR regulation and control abnormality, such as non-alcoholic fatty liver disease, and especially in treating non-alcoholic hepatitis, and may potentially be used in the treatment of diseases comprising diabetes, obesity, fibrotic diseases, cardiovascular diseases (comprising heart failure, atherosclerosis, and so on), kidney diseases (comprising chronic kidney disease, renal failure, and so on), and brain degenerative diseases (comprising Alzheimer's disease and so on), having great application value.


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