The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2022
Filed:
Mar. 25, 2020
Applicant:
Venenum Biodesign, Llc, Hamilton, NJ (US);
Inventors:
Jeffrey J. Letourneau, East Windsor, NJ (US);
Kiruthika Selvarangan Elamparuthi, Princeton Junction, NJ (US);
Chia-Yu Huang, West Windsor, NJ (US);
Venugopalareddy Bommireddy Venkata, Princeton Junction, NJ (US);
Assignee:
Venenum Biodesign, LLC, Hamilton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); A61K 31/551 (2006.01); C07D 487/04 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 35/00 (2018.01); A61K 45/06 (2013.01);
Abstract
The present invention provides compounds of Formula I wherein X, R, R, Rand Rare as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are effective at modulating the TREX1 protein and thus can be used as medicaments for treating or preventing disorders affected by the inhibition of TREX1.