The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2022
Filed:
May. 30, 2016
Applicant:
East China University of Science and Technology, Shanghai, CN;
Inventors:
Honglin Li, Shanghai, CN;
Yufang Xu, Shanghai, CN;
Zhenjiang Zhao, Shanghai, CN;
Wei Zhou, Shanghai, CN;
Yuqiong Xu, Shanghai, CN;
Deheng Sun, Shanghai, CN;
Xia Wang, Shanghai, CN;
Zhuo Chen, Shanghai, CN;
Assignee:
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61K 31/519 (2006.01); C07D 475/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/519 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07D 475/00 (2013.01);
Abstract
The present invention relates to a pteridinone derivative serving as an EGFR inhibitor and use thereof. Specifically, the present invention relates to a compound represented by the following formula I, pharmaceutical composition comprising the compound of the following formula I, and use of the compound in preparation of drugs for treating EGFR-mediated diseases or inhibiting EGFR.