The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Aug. 07, 2017
Applicants:

Commissariat a L'energie Atomique ET Aux Energies Alternatives, Paris, FR;

Universite Grenoble Alpes, St Martin d'Heres, FR;

Universite D'aix Marseille, Marseilles, FR;

Inventors:

Marie-Odile Fauvarque, Seyssins, FR;

Magda Mortier, Grenoble, FR;

Catherine Pillet, Vif, FR;

Carmen Aguilar, Grenoble, FR;

Emmanuelle Soleilhac, St Etienne de Crossey, FR;

Caroline Barette, Sassenage, FR;

Vincent Remusat, Marseilles, FR;

Thierry Terme, Arles, FR;

Patrice Vanelle, Marseilles, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 263/62 (2006.01); C07D 241/38 (2006.01); A61P 35/00 (2006.01); A61K 31/498 (2006.01); A61K 31/423 (2006.01); C07D 241/52 (2006.01); C07D 263/60 (2006.01); C07D 403/14 (2006.01); C07D 221/06 (2006.01); C07D 263/52 (2006.01);
U.S. Cl.
CPC ...
C07D 241/52 (2013.01); A61P 35/00 (2018.01); C07D 221/06 (2013.01); C07D 241/38 (2013.01); C07D 263/52 (2013.01); C07D 263/60 (2013.01); C07D 263/62 (2013.01); C07D 403/14 (2013.01);
Abstract

The present invention concerns heterocyclic naphthoquinones derivatives for use in the treatment of Cushing disease and other cancers, in particular via the inhibition of Ubiquitin Specific Proteases (USP) 8 and/or 2.


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