The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2022
Filed:
Apr. 25, 2016
Applicant:
Haemalogix Pty. Ltd., Eveleigh, AU;
Inventors:
Kenneth Micklethwaite, Westmead, AU;
Rosanne Dunn, Eveleigh, AU;
David Gottlieb, Westmead, AU;
Grant Logan, Westmead, AU;
Assignee:
HAEMALOGIX PTY. LTD., Eveleigh, AU;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/30 (2006.01); A61K 38/20 (2006.01); C07K 14/725 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C07K 14/54 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/395 (2013.01); A61K 35/17 (2013.01); A61K 38/204 (2013.01); C07K 14/5412 (2013.01); C07K 14/5434 (2013.01); C07K 14/7051 (2013.01); C07K 14/70521 (2013.01); C07K 16/2887 (2013.01); C07K 16/2896 (2013.01); C07K 16/30 (2013.01); C12N 5/0636 (2013.01); A61K 2039/505 (2013.01); C07K 2317/53 (2013.01); C07K 2317/56 (2013.01); C07K 2319/035 (2013.01); C12N 2510/00 (2013.01);
Abstract
The present invention provides compositions and methods for treating KMA-expressing malignancies including chimeric antigen receptors (CARs) and T cells containing CARs (CAR T-cells). The invention also provides methods and compositions comprising CAR T-cells co-expressing other anti-tumoral agents including cytokines and antibodies.