The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 19, 2022

Filed:

Nov. 24, 2015
Applicant:

Curadigm Sas, Paris, FR;

Inventors:

Agnes Pottier, Paris, FR;

Matthieu Germain, Champigny sur Marne, FR;

Laurence Poul, Paris, FR;

Marion Paolini, Neuilly sur Seine, FR;

Marie-Edith Meyre, Saint Mande, FR;

Assignee:

CURADIGM SAS, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 9/51 (2006.01); A61K 9/00 (2006.01); A61K 31/37 (2006.01); A61K 45/06 (2006.01); C07D 491/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 9/51 (2013.01); A61K 9/513 (2013.01); A61K 31/37 (2013.01); A61K 45/06 (2013.01); C07D 491/14 (2013.01); A61K 2121/00 (2013.01);
Abstract

The present disclosure generally relates to the field of medicine. The present invention more specifically relates to a pharmaceutical composition comprising the combination of (i) at least one biocompatible nanoparticle comprising, or consisting in, at least one natural compound which is an inhibitor of a human CYP enzyme, the longest dimension of said nanoparticle being of at least 4 nm and less than 100 nm, and (ii) at least one compound of interest, typically at least one pharmaceutical compound, to be administered to a subject in need of such at least one compound of interest, wherein the combination of the at least one biocompatible nanoparticle and of the at least one compound of interest potentiates the at least one compound of interest's bioavailability. The at least one biocompatible nanoparticle is to be administered to the subject separately from the at least one compound of interest (preferably before), typically with an interval of between at least about 5 minutes (preferably more than about 5 minutes) and about 72 hours.


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