The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 13, 2018
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
Ivan J. Dmochowski, Philadelphia, PA (US);
Yanfei Wang, Boston, MA (US);
Benjamin W. Roose, Philadelphia, PA (US);
Serge Zemerov, Cherry Hill, NJ (US);
Zhuangyu Zhao, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 49/14 (2006.01); G01R 33/28 (2006.01); C01B 23/00 (2006.01); A61K 49/18 (2006.01); G01R 33/62 (2006.01); G16H 50/20 (2018.01); G01R 33/56 (2006.01);
U.S. Cl.
CPC ...
G01R 33/282 (2013.01); A61K 49/0008 (2013.01); A61K 49/0056 (2013.01); A61K 49/14 (2013.01); A61K 49/183 (2013.01); C01B 23/0005 (2013.01); G01R 33/5601 (2013.01); G01R 33/62 (2013.01); G16H 50/20 (2018.01);
Abstract
The present invention relates to compositions and methods using protein reporters as imaging agents inXe NMR and MRI applications. It is described that bla and MBP are genetically-encoded proteins that induce a detectable chemical shift duringXe NMR, allowing for use as protein reporters in research and clinical applications.