The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Jan. 16, 2020
Applicant:

Wisconsin Alumni Research Foundation, Madison, WI (US);

Inventors:

Michael R. Sussman, Cross Plains, WI (US);

J. Leon Shohet, Madison, WI (US);

Faraz A. Choudhury, Madison, WI (US);

Joshua M. Blatz, Monona, WI (US);

Benjamin B. Minkoff, Madison, WI (US);

Daniel I. Benjamin, Madison, WI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01J 19/08 (2006.01); G01N 33/50 (2006.01); C12Q 1/6876 (2018.01); G01N 1/28 (2006.01); G01N 33/487 (2006.01); G01N 33/68 (2006.01); H05H 1/24 (2006.01); H01J 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/50 (2013.01); B01J 19/088 (2013.01); C12Q 1/6876 (2013.01); G01N 1/28 (2013.01); G01N 33/487 (2013.01); G01N 33/6848 (2013.01); H05H 1/24 (2013.01); B01J 2219/0809 (2013.01); B01J 2219/0894 (2013.01); G01N 2333/765 (2013.01); G01N 2333/90216 (2013.01); G01N 2333/91215 (2013.01); G01N 2440/00 (2013.01); H01J 49/0031 (2013.01);
Abstract

This disclosure provides methods, systems, and compositions of matter for studying solvent accessibility and three-dimensional structure of biological molecules. A plasma can be used to generate marker radicals, which can interact with a biological molecule and mark the solvent-accessible portions of the biological molecule.


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