The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Apr. 13, 2018
Applicant:

Imba—institut Für Molekulare Biotechnologie Gmbh, Vienna, AT;

Inventors:

Stefan L. Ameres, Klosterneuburg, AT;

Brian Reichholf, Vienna, AT;

Veronika A. Herzog, Vienna, AT;

Johannes Zuber, Vienna, AT;

Matthias Muhar, Vienna, AT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6869 (2018.01); C07H 21/00 (2006.01); C12N 15/11 (2006.01); C12Q 1/6806 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6869 (2013.01); C07H 21/00 (2013.01); C12N 15/11 (2013.01); C12Q 1/6806 (2013.01); C12N 2310/00 (2013.01);
Abstract

A method of identifying a polynucleic acid (PNA) is presented, including the steps of providing a PNA; modifying one or more nucleobases of the PNA by addition or removal of a hydrogen bonding partner, thereby altering the base pairing capacity of the one or more nucleobases; base pairing a complementary nucleic acid to the PNA, including base pairing to at least one modified nucleobase; identifying the sequence of the complementary nucleic acid at least at the position that is complementary to at least one modified nucleobase.


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