The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 12, 2022

Filed:

Jan. 22, 2018
Applicants:

Jeunghoon Lee, Boise, ID (US);

Bernard Yurke, Boise, ID (US);

Elton Graugnard, Boise, ID (US);

Will Hughes, Blacksburg, ID (US);

Bert Huttanus, Blacksburg, VA (US);

Inventors:

Jeunghoon Lee, Boise, ID (US);

Bernard Yurke, Boise, ID (US);

Elton Graugnard, Boise, ID (US);

Will Hughes, Blacksburg, ID (US);

Bert Huttanus, Blacksburg, VA (US);

Assignee:

Boise State University, Boise, ID (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/682 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/682 (2013.01); C12Q 1/682 (2013.01); C12Q 2525/197 (2013.01); C12Q 2525/301 (2013.01); C12Q 2563/137 (2013.01); C12Q 2563/155 (2013.01); C12Q 2565/113 (2013.01);
Abstract

The present invention provides compositions and methods for colorimetric detection schemes for detecting a variety of biomolecules. The compositions and methods employ DNA hybridization chain reaction for catalytic aggregation of gold nanoparticles. In this catalytic aggregation scheme, a single target DNA strand triggers the formation of multiple inter-particle linkages in contrast to the single linkage formed in conventional direct aggregation schemes.


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