The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Jun. 06, 2017
Applicant:
Cepheid, Sunnyvale, CA (US);
Inventors:
Sergey G. Lokhov, Seattle, WA (US);
Alexander A. Gall, Woodinville, WA (US);
Vera Baraznenok, Sunnyvale, CA (US);
Ekaterina V. Viazovkina, Sunnyvale, CA (US);
Irina Shishkina, Sunnyvale, CA (US);
David H. Persing, San Martin, CA (US);
Assignee:
CEPHEID, Sunnyvale, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6853 (2018.01); C12Q 1/686 (2018.01); C12N 15/115 (2010.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6853 (2013.01); C12N 2310/16 (2013.01); C12N 2310/531 (2013.01); C12N 2310/532 (2013.01); C12N 2320/52 (2013.01); C12Q 2525/205 (2013.01);
Abstract
The present disclosure relates to aptamers for temperature-dependent reversible inhibition of thermostable polymerase activity in order to improve sensitivity and specificity of various reactions and assays involving hot start polynucleotide synthesis. Methods for use of the aptamers and related compositions and kits are also provided.