The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 2022
Filed:
Mar. 14, 2014
Applicant:
4basebio SL, Madrid, ES;
Inventors:
Angel J. Picher, Madrid, ES;
Luis Blanco, Madrid, ES;
Assignee:
4BASEBIO SL, Madrid, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12N 15/10 (2006.01); C12Q 1/686 (2018.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1252 (2013.01); C12N 15/102 (2013.01); C12P 19/34 (2013.01); C12Q 1/686 (2013.01); C12Y 207/07007 (2013.01);
Abstract
The present invention is directed to methods for replicating, amplifying, and sequencing of nucleic acids using the thermostable, bifunctional replicase 'TthPrimPol' fromHB27. The TthPrimPol enzyme is extremely tolerant to alterations of the nucleotides of the template nucleic acid. Therefore, in one aspect the invention discloses methods for replicating, amplifying and sequencing of damaged polynucleotide templates.